MRQLAB EXPLORATION MATRIX

Clinical Intent ➔ Physics Execution

Select a verified clinical pathology case to launch the Retromorphic Workbench instrument.

📍 Single voxel / water referenceAdvanced

Amide CEST CW Z-spectrum

Clinical Question: How does CW amide exchange create asymmetry in a backend-computed Z-spectrum?
Key Physics: Two-liquid-pool CW Bloch–McConnell saturation transfer
⚡ EPG-X CEST CW offset sweep
Launch Cockpit ➔
📍 Single voxel / water referenceAdvanced

Amide CEST pulsed Z-spectrum

Clinical Question: How does a pulsed saturation train change the backend-computed amide Z-spectrum versus CW?
Key Physics: Two-liquid-pool pulsed Bloch–McConnell saturation train
⚡ EPG-X CEST pulsed offset sweep
Launch Cockpit ➔
📍 Single voxel / water referenceAdvanced

Amine CEST CW Z-spectrum

Clinical Question: How does CW amine exchange create asymmetry in a backend-computed Z-spectrum?
Key Physics: Two-liquid-pool CW Bloch–McConnell saturation transfer
⚡ EPG-X CEST CW offset sweep
Launch Cockpit ➔
📍 Spectral observationAdvanced

¹H MR Spectroscopy

Clinical Question: Density-matrix engine unavailable
Key Physics: Not in v0.1
⚡ Unavailable
not in v0.1
📍 Non-proton nucleiAdvanced

X-nuclei Spectroscopy

Clinical Question: X-nuclei engine unavailable
Key Physics: Not in v0.1
⚡ Unavailable
not in v0.1
📍 Brain / White MatterFundamental

Multiple Sclerosis (MS) Plaque Contrast

Clinical Question: Why do demyelinating MS plaques appear hyperintense on T2 TSE while minimizing CSF partial volume artifacts?
Key Physics: T2 transverse relaxation differentiation + EPG stimulated echo preservation in TSE echo train
⚡ Brain T2 Turbo Spin Echo (TSE)
Launch Cockpit ➔
📍 Brain / VentriclesIntermediate

FLAIR Free-Water Attenuation

Clinical Question: How does Inversion Recovery null CSF signal to reveal periventricular lesions?
Key Physics: 180° Inversion Recovery null-crossing timing $TI = T1 \\ln(2)$
⚡ T2 Fluid Attenuated Inversion Recovery
not in v0.1
📍 Heart / Carotid ArteryAdvanced

Dark Blood

Clinical Question: How to completely suppress flowing luminal blood signal while preserving high SNR for carotid plaque wall?
Key Physics: Double Inversion Recovery (DIR) flow dephasing + slice selective re-inversion
⚡ Dark Blood Turbo Spin Echo (Uses: TSE)
Launch Cockpit ➔
📍 MyocardiumAdvanced

Myocardial Fibrosis MOLLI T1 Mapping

Clinical Question: How to quantify diffuse interstitial fibrosis via pixel-wise T1 relaxation fitting?
Key Physics: Look-Locker readout modification with modified EPG steady-state correction
⚡ Modified Look-Locker Inversion (MOLLI)
not in v0.1
📍 Abdomen / LiverIntermediate

Dixon Two-Point Water-Fat Separation

Clinical Question: How does chemical shift phase cycling separate fat from water parenchymal signals?
Key Physics: 3.5 ppm chemical shift $\\Delta f$ phase modulation between in-phase and out-of-phase echoes
⚡ Dual-Echo Fast Gradient Echo (GRE)
Launch Cockpit ➔
📍 Musculoskeletal / KneeFundamental

Knee Articular Cartilage T2 Mapping

Clinical Question: How does collagen matrix degradation correlate with multi-echo T2 prolongation?
Key Physics: Multi-echo Spin Echo CPMG decay curve exponential non-linear regression
⚡ Multi-Echo Spin Echo (MESE)
not in v0.1